InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ALOX15

Summary

InnateDB Protein

IDBP-758568.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ALOX15

Protein Name

Synonyms

12-LOX; 15-LOX-1; 15LOX-1;

Species

Homo sapiens

Ensembl Protein

ENSP00000460483

InnateDB Gene

IDBG-19074 (ALOX15)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005506	iron ion binding
GO:0005515	protein binding
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872	metal ion binding

Biological Process

GO:0055114

oxidation-reduction process

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR001024 PLAT/LH2 domain
IPR001885 Lipoxygenase, mammalian
IPR008976 Lipase/lipooxygenase, PLAT/LH2
IPR013819 Lipoxygenase, C-terminal

PFAM

PF01477
PF00305

PRINTS

PR00467
PR00087

PIRSF

SMART

SM00308

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3DTK1

UniProt Splice Variant

Entrez Gene

246

UniGene

Hs.73809

RefSeq

HUGO

HGNC:433

OMIM

152392

CCDS

HPRD

01067

IMGT

EMBL

AC118754 AK316126 CH471108

GenPept

BAH14497 EAW90427 EAW90428