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InnateDB Protein
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IDBP-759676.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ENGASE
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Protein Name
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000462333
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InnateDB Gene
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IDBG-71116 (ENGASE)
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Protein Structure
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| Function |
Endoglycosidase that releases N-glycans from glycoproteins by cleaving the beta-1,4-glycosidic bond in the N,N'-diacetylchitobiose core. Involved in the processing of free oligosaccharides in the cytosol. {ECO:0000269PubMed:12114544}.
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| Subcellular Localization |
Cytoplasm, cytosol {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
Widely expressed. Expressed at higher level in thymus and spleen. {ECO:0000269PubMed:12114544}.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
| Experimentally validated |
| Total |
2
[view]
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| Protein-Protein |
2
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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Molecular Function |
| Accession |
GO Term |
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GO:0033925
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mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
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| Biological Process |
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR001357
BRCT domain
IPR005201
Glycoside hydrolase, family 85
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| PFAM |
PF00533
PF12738
PF03644
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| PRINTS |
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| PIRSF |
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| SMART |
SM00292
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q8NFI3
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| PhosphoSite |
PhosphoSite-Q8NFI3
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
64772
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| UniGene |
Hs.29288
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| RefSeq |
NP_001036038
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| HUGO |
HGNC:24622
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| OMIM |
611898
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| CCDS |
CCDS42394
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| HPRD |
10978
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| IMGT |
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| EMBL |
AF512564
AK025518
AL110283
BC024213
CH471099
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| GenPept |
AAH24213
AAM80487
BAB15158
CAH56405
EAW89562
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Version 5.4