Homo sapiens Protein: NF1
Summary
InnateDB Protein IDBP-760012.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NF1
Protein Name
Synonyms NFNS; VRNF; WSS;
Species Homo sapiens
Ensembl Protein ENSP00000462408
InnateDB Gene IDBG-39462 (NF1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 26 [view]
Protein-Protein 23 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005099 Ras GTPase activator activity
Biological Process
GO:0007165 signal transduction
GO:0032320 positive regulation of Ras GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID
InterPro IPR001936 Ras GTPase-activating protein
IPR008936 Rho GTPase activation protein
PFAM PF00616
PRINTS
PIRSF
SMART SM00323
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9UMU3
UniProt Splice Variant
Entrez Gene 4763
UniGene Hs.721732
RefSeq
HUGO HGNC:7765
OMIM 613113
CCDS
HPRD 01203
IMGT
EMBL AC004222 AC079915 AC134669 AC135724 AC138207 AC139072 CH471147 U17084
GenPept AAA56765 EAW80267 EAW80269