Version 5.4
Homo sapiens Protein: ITGB1BP2
Summary
InnateDB Protein IDBP-76022.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ITGB1BP2
Protein Name integrin beta 1 binding protein (melusin) 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000362935
InnateDB Gene IDBG-76020 (ITGB1BP2)
Protein Structure
UniProt Annotation
Function May play a role during maturation and/or organization of muscles cells.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in skeletal and cardiac muscles but not in other tissues.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005178 integrin binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0017124 SH3 domain binding
Biological Process
GO:0007165 signal transduction
GO:0007517 muscle organ development
Cellular Component
GO:0030018 Z disc
Protein Structure and Domains
PDB ID
InterPro IPR007051 Cysteine/histidine-rich domain
IPR007052 CS domain
IPR008978 HSP20-like chaperone
PFAM PF04968
PF04969
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UKP3
PhosphoSite PhosphoSite-Q9UKP3
TrEMBL
UniProt Splice Variant
Entrez Gene 26548
UniGene
RefSeq NP_036410
HUGO HGNC:6154
OMIM 300332
CCDS CCDS14411
HPRD 02271
IMGT
EMBL AF110225 AF140690
GenPept AAF01676 AAL36913

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca