Version 5.4
Homo sapiens Protein: RUFY2
Summary
InnateDB Protein IDBP-76071.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RUFY2
Protein Name RUN and FYVE domain containing 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000265865
InnateDB Gene IDBG-76069 (RUFY2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in brain, lung and testis. {ECO:0000269PubMed:11877430}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 8 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000306 FYVE zinc finger
IPR011011 Zinc finger, FYVE/PHD-type
IPR017455 Zinc finger, FYVE-related
PFAM PF01363
PRINTS
PIRSF
SMART SM00064
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q8WXA3
TrEMBL X6R3F0
UniProt Splice Variant
Entrez Gene 55680
UniGene Hs.653144
RefSeq
HUGO HGNC:19761
OMIM 610328
CCDS
HPRD 11526
IMGT
EMBL AC016395 AL136233
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca