InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IFT52

Summary

InnateDB Protein

IDBP-76123.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IFT52

Protein Name

intraflagellar transport 52 homolog (Chlamydomonas)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000362121

InnateDB Gene

IDBG-76119 (IFT52)

Protein Structure

UniProt Annotation

Function

Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. {ECO:0000250}.

Subcellular Localization

Cell projection, cilium.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008022	protein C-terminus binding

Biological Process

GO:0001841	neural tube formation
GO:0001947	heart looping
GO:0007224	smoothened signaling pathway
GO:0007368	determination of left/right symmetry
GO:0009953	dorsal/ventral pattern formation
GO:0042733	embryonic digit morphogenesis
GO:0050680	negative regulation of epithelial cell proliferation
GO:0060271	cilium morphogenesis
GO:0070613	regulation of protein processing

Cellular Component

GO:0005813	centrosome
GO:0005929	cilium
GO:0030992	intraciliary transport particle B
GO:0031514	motile cilium
GO:0032391	photoreceptor connecting cilium
GO:0044292	dendrite terminus
GO:0097542	ciliary tip
GO:0097546	ciliary base