Version 5.4
Homo sapiens Protein: NUP88
Summary
InnateDB Protein IDBP-762053.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUP88
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000458954
InnateDB Gene IDBG-21334 (NUP88)
Protein Structure
UniProt Annotation
Function Essential component of nuclear pore complex.
Subcellular Localization Nucleus, nuclear pore complex.
Disease Associations
Tissue Specificity Ubiquitous.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 29 [view]
Protein-Protein 27 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
Biological Process
GO:0000278 mitotic cell cycle
GO:0005975 carbohydrate metabolic process
GO:0007077 mitotic nuclear envelope disassembly
GO:0008645 hexose transport
GO:0010827 regulation of glucose transport
GO:0015031 protein transport
GO:0015758 glucose transport
GO:0016032 viral process
GO:0019221 cytokine-mediated signaling pathway
GO:0044281 small molecule metabolic process
GO:0051028 mRNA transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR019321 Nucleoporin Nup88
PFAM PF10168
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99567
PhosphoSite PhosphoSite-Q99567
TrEMBL I3L245
UniProt Splice Variant
Entrez Gene 4927
UniGene Hs.743433
RefSeq NP_002523
HUGO HGNC:8067
OMIM 602552
CCDS CCDS11070
HPRD 03974
IMGT
EMBL AC004148 AC015727 BC000335 CH471108 Y08612
GenPept AAH00335 CAA69904 EAW90340 EAW90342

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca