Version 5.4
Homo sapiens Protein: NLRP8
Summary
InnateDB Protein IDBP-762196.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NLRP8
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000468121
InnateDB Gene IDBG-71259 (NLRP8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005524 ATP binding
Biological Process
GO:0045087 innate immune response (InnateDB)
GO:0070997 neuron death
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR003590 Leucine-rich repeat, ribonuclease inhibitor subtype
IPR004020 DAPIN domain
IPR007111 NACHT nucleoside triphosphatase
IPR011029 Death-like domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF02758
PRINTS
PIRSF
SMART SM00368
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86W28
PhosphoSite PhosphoSite-Q86W28
TrEMBL
UniProt Splice Variant
Entrez Gene 126205
UniGene Hs.446925
RefSeq XP_005258568
HUGO HGNC:22940
OMIM 609659
CCDS
HPRD 14807
IMGT
EMBL AY154463 BK001109
GenPept AAO18159 DAA01242

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca