Version 5.4
Homo sapiens Protein: CACNA1A
Summary
InnateDB Protein IDBP-762350.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CACNA1A
Protein Name
Synonyms APCA; BI; CACNL1A4; CAV2.1; EA2; FHM; HPCA; MHP; MHP1; SCA6;
Species Homo sapiens
Ensembl Protein ENSP00000465598
InnateDB Gene IDBG-31996 (CACNA1A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 106 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 106 [view]
Protein-Protein 106 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005245 voltage-gated calcium channel activity
Biological Process
GO:0006811 ion transport
GO:0034765 regulation of ion transmembrane transport
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005891 voltage-gated calcium channel complex
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR005821 Ion transport domain
IPR014873 Voltage-dependent calcium channel, alpha-1 subunit, IQ domain
PFAM PF00520
PF08763
PRINTS
PIRSF
SMART SM01062
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9UHM9
UniProt Splice Variant
Entrez Gene 773
UniGene Hs.729638
RefSeq
HUGO HGNC:1388
OMIM 601011
CCDS
HPRD
IMGT
EMBL AC005305 AC005513 AC008540 AC011446 AC022436 AC026805 AC093062 AC098781 AC124224 AF144098
GenPept AAF03935

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca