InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: EIF1

Summary

InnateDB Protein

IDBP-762404.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EIF1

Protein Name

Synonyms

A121; EIF-1; EIF1A; ISO1; SUI1;

Species

Homo sapiens

Ensembl Protein

ENSP00000466321

InnateDB Gene

IDBG-49651 (EIF1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	12 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003743	translation initiation factor activity
GO:0008135	translation factor activity, nucleic acid binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006413	translational initiation
GO:0006446	regulation of translational initiation
GO:0006950	response to stress

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001950 Translation initiation factor SUI1
IPR005874 Eukaryotic translation initiation factor SUI1

PFAM

PF01253

PRINTS

PIRSF

PIRSF004499

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q6IAV3

UniProt Splice Variant

Entrez Gene

102723417

UniGene

Hs.740876

RefSeq

HUGO

HGNC:3249

OMIM

CCDS

HPRD

15449

IMGT

EMBL

AC130686 AF083441 AF100737 AJ012375 AK311862 BC005118 BC008710 BT006645 CH471152 CR457051 L26247

GenPept

AAA60602 AAD19900 AAD52028 AAH05118 AAH08710 AAP35291 BAG34803 CAD66615 CAG33332 EAW60754