InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: EIF5A

Summary

InnateDB Protein

IDBP-762605.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EIF5A

Protein Name

Synonyms

EIF-5A; EIF5A1; eIF5AI;

Species

Homo sapiens

Ensembl Protein

ENSP00000461688

InnateDB Gene

IDBG-24314 (EIF5A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.

Experimentally validated
Total	37 [view]
Protein-Protein	37 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003746	translation elongation factor activity
GO:0043022	ribosome binding

Biological Process

GO:0006452	translational frameshifting
GO:0008612	peptidyl-lysine modification to peptidyl-hypusine
GO:0045901	positive regulation of translational elongation
GO:0045905	positive regulation of translational termination

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR001884 Translation elongation factor IF5A
IPR005824 KOW
IPR008991 Translation protein SH3-like domain
IPR012340 Nucleic acid-binding, OB-fold
IPR020189 Translation elongation factor, IF5A C-terminal

PFAM

PF00467
PF01287

PRINTS

PIRSF

PIRSF003025

SMART

SM00739

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt