InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SCN4A

Summary

InnateDB Protein

IDBP-762615.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SCN4A

Protein Name

Synonyms

HOKPP2; HYKPP; HYPP; Na(V)1.4; NAC1A; Nav1.4; SkM1;

Species

Homo sapiens

Ensembl Protein

ENSP00000463963

InnateDB Gene

IDBG-64440 (SCN4A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005248	voltage-gated sodium channel activity
GO:0005515	protein binding

Biological Process

GO:0006811	ion transport
GO:0006814	sodium ion transport
GO:0034765	regulation of ion transmembrane transport
GO:0035725	sodium ion transmembrane transport
GO:0055085	transmembrane transport

Cellular Component

GO:0001518	voltage-gated sodium channel complex
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000048 IQ motif, EF-hand binding site
IPR001696 Voltage gated sodium channel, alpha subunit
IPR003915 Polycystic kidney disease type 2 protein
IPR005821 Ion transport domain
IPR008052 Voltage gated sodium channel, alpha-4 subunit, mammalian
IPR010526 Sodium ion transport-associated
IPR013122 Polycystin cation channel, PKD1/PKD2

PFAM

PF00612
PF00520
PF06512
PF08016

PRINTS

PR00170
PR01433
PR01665

PIRSF

SMART

SM00015

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt