InnateDB Protein
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IDBP-763108.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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MIS12
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Protein Name
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000461252
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InnateDB Gene
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IDBG-21731 (MIS12)
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Protein Structure
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Function |
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis. {ECO:0000269PubMed:12515822, ECO:0000269PubMed:15502821, ECO:0000269PubMed:16585270}.
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Subcellular Localization |
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 48 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
48
[view]
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Protein-Protein |
47
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR008685
Centromere protein Mis12
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PFAM |
PF05859
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9H081
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PhosphoSite |
PhosphoSite-
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TrEMBL |
I3L4K6
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UniProt Splice Variant |
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Entrez Gene |
79003
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UniGene |
Hs.743815
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RefSeq |
NP_001245149
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HUGO |
HGNC:24967
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OMIM |
609178
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CCDS |
CCDS11074
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HPRD |
12379
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IMGT |
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EMBL |
AC004148
AC055839
AK056072
AL136906
BC000229
CR533460
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GenPept |
AAH00229
CAB66840
CAG38491
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