Version 5.4
Homo sapiens Protein: RNF112
Summary
InnateDB Protein IDBP-763504.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNF112
Protein Name
Synonyms BFP; ZNF179;
Species Homo sapiens
Ensembl Protein ENSP00000454919
InnateDB Gene IDBG-34776 (RNF112)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Predominantly expressed in brain. {ECO:0000269PubMed:10574464}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0008270 zinc ion binding
Biological Process
GO:0006184 GTP catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001841 Zinc finger, RING-type
IPR015894 Guanylate-binding protein, N-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF13639
PF14634
PF02263
PRINTS
PIRSF
SMART SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9ULX5
PhosphoSite PhosphoSite-Q9ULX5
TrEMBL J3QRB8
UniProt Splice Variant
Entrez Gene 7732
UniGene Hs.189482
RefSeq NP_009079
HUGO HGNC:12968
OMIM 601237
CCDS CCDS58529
HPRD 03140
IMGT
EMBL AB026054 AC004448 AF054587 BC053989
GenPept AAC08584 AAH53989 BAA84698

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca