Version 5.4
| Homo sapiens Protein: PIRT | |||
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| Summary | |||
| InnateDB Protein | IDBP-763515.3 | ||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||
| Gene Symbol | PIRT | ||
| Protein Name | |||
| Synonyms | |||
| Species | Homo sapiens | ||
| Ensembl Protein | ENSP00000462046 | ||
| InnateDB Gene | IDBG-301062 (PIRT) | ||
| Protein Structure |
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| UniProt Annotation | |||
| Function | Regulatory subunit of TRPV1, a molecular sensor of noxious heat and capsaicin. Positively regulates TRPV1 channel activity via phosphatidylinositol 4,5-bisphosphate (PIP2). Binds various phosphoinositide, including phosphatidylinositol 4,5- bisphosphate (PIP2), but not phosphatidylinositol (PI) (By similarity). {ECO:0000250}. | ||
| Subcellular Localization | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. | ||
| Disease Associations | |||
| Tissue Specificity | |||
| Comments | |||
| Interactions | |||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||
| PDB ID | |||
| InterPro | |||
| PFAM | |||
| PRINTS | |||
| PIRSF | |||
| SMART | |||
| TIGRFAMs | |||
| Post-translational Modifications | |||
| Modification | |||
| Cross-References | |||
| SwissProt | P0C851 | ||
| PhosphoSite | PhosphoSite- | ||
| TrEMBL | |||
| UniProt Splice Variant | |||
| Entrez Gene | 644139 | ||
| UniGene | Hs.553909 | ||
| RefSeq | NP_001094857 | ||
| HUGO | HGNC:37239 | ||
| OMIM | 612068 | ||
| CCDS | CCDS45614 | ||
| HPRD | |||
| IMGT | |||
| EMBL | AC015908 AK299808 CH471108 DC332889 | ||
| GenPept | BAH13134 EAW89989 | ||