Version 5.4
Homo sapiens Protein: SCPEP1
Summary
InnateDB Protein IDBP-764418.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCPEP1
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000458587
InnateDB Gene IDBG-60286 (SCPEP1)
Protein Structure
UniProt Annotation
Function May be involved in vascular wall and kidney homeostasis. {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004185 serine-type carboxypeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0042573 retinoic acid metabolic process
GO:0045776 negative regulation of blood pressure
GO:0045909 positive regulation of vasodilation
Cellular Component
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001563 Peptidase S10, serine carboxypeptidase
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00450
PRINTS PR00724
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9HB40
PhosphoSite PhosphoSite-Q9HB40
TrEMBL I3L506
UniProt Splice Variant
Entrez Gene 59342
UniGene Hs.514950
RefSeq
HUGO HGNC:29507
OMIM
CCDS
HPRD 10194
IMGT
EMBL AC004584 AC007114 AF113214 AF282618 AK027373 AY358559 BC010078 BC072405
GenPept AAG16692 AAG39285 AAH72405 AAQ88923 BAB55069

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca