InnateDB Protein
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IDBP-764605.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PTRH2
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Protein Name
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000464327
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InnateDB Gene
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IDBG-61806 (PTRH2)
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Protein Structure
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Function |
The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis. {ECO:0000250}.Promotes caspase-independent apoptosis by regulating the function of two transcriptional regulators, AES and TLE1. {ECO:0000269PubMed:15006356}.
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Subcellular Localization |
Mitochondrion.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
20
[view]
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Protein-Protein |
19
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR002833
Peptidyl-tRNA hydrolase, PTH2
IPR023476
Peptidyl-tRNA hydrolase II domain
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PFAM |
PF01981
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9Y3E5
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PhosphoSite |
PhosphoSite-Q9Y3E5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
51651
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UniGene |
Hs.12677
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RefSeq |
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HUGO |
HGNC:24265
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OMIM |
608625
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CCDS |
CCDS11618
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HPRD |
12273
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IMGT |
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EMBL |
AF151905
AK098219
AL137322
BC006807
CH471109
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GenPept |
AAD34142
AAH06807
BAG53596
CAB70696
EAW94394
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