Homo sapiens Protein: TEAD2
Summary
InnateDB Protein IDBP-764853.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TEAD2
Protein Name
Synonyms ETF; TEAD-2; TEF-4; TEF4;
Species Homo sapiens
Ensembl Protein ENSP00000472109
InnateDB Gene IDBG-62529 (TEAD2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0001570 vasculogenesis
GO:0001843 neural tube closure
GO:0003143 embryonic heart tube morphogenesis
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0030903 notochord development
GO:0035329 hippo signaling
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048339 paraxial mesoderm development
GO:0048368 lateral mesoderm development
GO:0060548 negative regulation of cell death
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Protein Structure and Domains
PDB ID
InterPro IPR000818 TEA/ATTS
IPR016361 Transcriptional enhancer factor
IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain
PFAM PF01285
PRINTS PR00065
PIRSF PIRSF002603
SMART SM00426
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL M0R290
UniProt Splice Variant
Entrez Gene 8463
UniGene Hs.733534
RefSeq NP_001243590
HUGO HGNC:11715
OMIM 601729
CCDS CCDS59406
HPRD
IMGT
EMBL AC010524
GenPept