Version 5.4
Homo sapiens Protein: NINJ1
Summary
InnateDB Protein IDBP-76489.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NINJ1
Protein Name ninjurin 1
Synonyms NIN1; NINJURIN;
Species Homo sapiens
Ensembl Protein ENSP00000364595
InnateDB Gene IDBG-76487 (NINJ1)
Protein Structure
UniProt Annotation
Function Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Cell adhesion requires divalent cations.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Widely expressed in both adult and embryonic tissues, primarily those of epithelial origin.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001954 positive regulation of cell-matrix adhesion
GO:0007155 cell adhesion
GO:0007399 nervous system development
GO:0042246 tissue regeneration
GO:1990384 hyaloid vascular plexus regression
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR007007 Ninjurin
PFAM PF04923
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q92982
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 4814
UniGene
RefSeq NP_004139
HUGO HGNC:7824
OMIM 602062
CCDS CCDS6703
HPRD 03639
IMGT
EMBL AF029251 AL451065 BC000298 BC004440 BC019336 BC048212 BT007164 CH471089 U72661 U91512
GenPept AAB17560 AAC14593 AAC39574 AAH00298 AAH04440 AAH19336 AAH48212 AAP35828 CAI95111 EAW62856

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca