InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SMARCA4

Summary

InnateDB Protein

IDBP-764933.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SMARCA4

Protein Name

Synonyms

BAF190; BAF190A; BRG1; hSNF2b; MRD16; RTPS2; SNF2; SNF2L4; SNF2LB; SWI2;

Species

Homo sapiens

Ensembl Protein

ENSP00000467200

InnateDB Gene

IDBG-28592 (SMARCA4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 331 experimentally validated interaction(s) in this database.
They are also associated with 92 interaction(s) predicted by orthology.

Experimentally validated
Total	331 [view]
Protein-Protein	305 [view]
Protein-DNA	24 [view]
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	92 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0004386	helicase activity
GO:0005524	ATP binding
GO:0042393	histone binding

Biological Process

GO:0008152	metabolic process
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus

Protein Structure and Domains

PDB ID

InterPro

IPR001650 Helicase, C-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00271

PRINTS

PIRSF

SMART

SM00490

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

K7EP28

UniProt Splice Variant

Entrez Gene

6597

UniGene

Hs.741659

RefSeq

HUGO

HGNC:11100

OMIM

603254

CCDS

HPRD

04459

IMGT

EMBL

AC006127 AC011442 AC011485

GenPept