Version 5.4
Homo sapiens Protein: KLK3
Summary
InnateDB Protein IDBP-765296.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KLK3
Protein Name
Synonyms APS; hK3; KLK2A1; PSA;
Species Homo sapiens
Ensembl Protein ENSP00000472411
InnateDB Gene IDBG-64971 (KLK3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.
Experimentally validated
Total 34 [view]
Protein-Protein 9 [view]
Protein-DNA 25 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001254 Peptidase S1
IPR009003 Trypsin-like cysteine/serine peptidase domain
PFAM PF00089
PRINTS
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL M0R294
UniProt Splice Variant
Entrez Gene 354
UniGene Hs.600536
RefSeq
HUGO HGNC:6364
OMIM 176820
CCDS
HPRD 01461
IMGT
EMBL AC011523 CH471135
GenPept EAW71925

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca