InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NUP35

Summary

InnateDB Protein

IDBP-76941.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NUP35

Protein Name

nucleoporin 35kDa

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000295119

InnateDB Gene

IDBG-76939 (NUP35)

Protein Structure

UniProt Annotation

Function

Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs). Can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. May play a role in the association of MAD1 with the NPC. {ECO:0000269PubMed:15703211}.

Subcellular Localization

Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein. Note=Tightly associated with the nuclear membrane and lamina.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	6 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0000278	mitotic cell cycle
GO:0005975	carbohydrate metabolic process
GO:0007077	mitotic nuclear envelope disassembly
GO:0008645	hexose transport
GO:0010827	regulation of glucose transport
GO:0015031	protein transport
GO:0015758	glucose transport
GO:0016032	viral process
GO:0019221	cytokine-mediated signaling pathway
GO:0044281	small molecule metabolic process
GO:0051028	mRNA transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005634	nucleus
GO:0005635	nuclear envelope
GO:0005643	nuclear pore
GO:0005886	plasma membrane
GO:0031965	nuclear membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0045111	intermediate filament cytoskeleton