Version 5.4
Homo sapiens Protein: ZC3H15
Summary
InnateDB Protein IDBP-77030.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZC3H15
Protein Name zinc finger CCCH-type containing 15
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000338788
InnateDB Gene IDBG-77028 (ZC3H15)
Protein Structure
UniProt Annotation
Function Protects DRG1 from proteolytic degradation. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:15676025, ECO:0000269PubMed:19819225}. Nucleus {ECO:0000250}. Note=The DRG1-DFRP2/ZC3H15 complex associates with polysomes.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 26 [view]
Protein-Protein 25 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0019221 cytokine-mediated signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000571 Zinc finger, CCCH-type
PFAM PF00642
PRINTS
PIRSF
SMART SM00356
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WU90
PhosphoSite PhosphoSite-Q8WU90
TrEMBL
UniProt Splice Variant
Entrez Gene 55854
UniGene
RefSeq NP_060941
HUGO HGNC:29528
OMIM
CCDS CCDS42791
HPRD 13988
IMGT
EMBL AC018867 AF109366 AF161421 AF220184 AF289586 AK001901 BC021102 CH471058
GenPept AAF28981 AAF67649 AAH21102 AAL55770 AAQ13514 AAX88885 BAA91968 EAX10935 EAX10936

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca