Version 5.4
Homo sapiens Protein: CCHCR1
Summary
InnateDB Protein IDBP-77146.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CCHCR1
Protein Name coiled-coil alpha-helical rod protein 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000365442
InnateDB Gene IDBG-77144 (CCHCR1)
Protein Structure
UniProt Annotation
Function May be a regulator of keratinocyte proliferation or differentiation.
Subcellular Localization Cytoplasm. Nucleus.
Disease Associations
Tissue Specificity Found in all tissues tested, abundantly expressed in heart, liver, skeletal muscle, kidney and pancreas, and to a lesser extent in lung and placenta. Overexpressed in keratinocytes of psoriatic lesions.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 12 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007275 multicellular organismal development
GO:0030154 cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005814 centriole
Protein Structure and Domains
PDB ID
InterPro IPR009800 Alpha helical coiled-coil rod
PFAM PF07111
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8TD31
PhosphoSite PhosphoSite-Q8TD31
TrEMBL E9PGB6
UniProt Splice Variant
Entrez Gene 54535
UniGene Hs.485075
RefSeq NP_061925
HUGO HGNC:13930
OMIM 605310
CCDS CCDS4695
HPRD 05607
IMGT
EMBL AB029331 AB029343 AB088104 AF216493 AK000204 AK000217 AK000533 AK295494 AL662833 AL662844 AL773544 AY029160 BA000025 BC110535 CR753819 EF055706 EF055734 EF055744 EF055788 EF055792
GenPept AAF74221 AAI10536 AAK55759 ABO30712 ABO30740 ABO30750 ABO30794 ABO30798 BAA81890 BAA82158 BAA91007 BAA91016 BAA91236 BAB63313 BAC54937 BAG58414 CAI17405 CAI18328 CAI18483 CAM25639 CAQ10597 CAX15089

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca