InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SAR1A

Summary

InnateDB Protein

IDBP-77277.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SAR1A

Protein Name

SAR1 homolog A (S. cerevisiae)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000362333

InnateDB Gene

IDBG-77267 (SAR1A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	12 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0004871	signal transducer activity
GO:0005525	GTP binding
GO:0019001	guanyl nucleotide binding
GO:0031683	G-protein beta/gamma-subunit complex binding

Biological Process

GO:0006886	intracellular protein transport
GO:0007186	G-protein coupled receptor signaling pathway

Cellular Component

GO:0005622

intracellular

Protein Structure and Domains

PDB ID

InterPro

IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit
IPR006687 Small GTPase superfamily, SAR1-type
IPR006689 Small GTPase superfamily, ARF/SAR type
IPR019009 Signal recognition particle receptor, beta subunit
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00503
PF00025
PF09439

PRINTS

PR00318
PR00328

PIRSF

SMART

SM00275
SM00178

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt