Version 5.4
Homo sapiens Protein: MFSD6
Summary
InnateDB Protein IDBP-77533.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MFSD6
Protein Name major facilitator superfamily domain containing 6
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000281416
InnateDB Gene IDBG-77531 (MFSD6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Widely expressed. Expression levels in peripheral blood mononuclear cells are highly variable between individuals, including no expression at all. {ECO:0000269PubMed:20123006}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
PFAM PF07690
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ZSS7
PhosphoSite PhosphoSite-Q6ZSS7
TrEMBL C9JJH2
UniProt Splice Variant
Entrez Gene 54842
UniGene Hs.741703
RefSeq XP_005246711
HUGO HGNC:24711
OMIM 613476
CCDS CCDS2306
HPRD 13369
IMGT
EMBL AB472299 AC092178 AC093388 AK000167 AK127176 AK302647 AK302753 BC050537 CH471058
GenPept AAH50537 AAY24173 BAA90987 BAC86869 BAH13768 BAH13796 BAI82196 EAX10867 EAX10868

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca