Homo sapiens Protein: SPOCK2
Summary
InnateDB Protein IDBP-77815.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPOCK2
Protein Name sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
Synonyms testican-2;
Species Homo sapiens
Ensembl Protein ENSP00000321108
InnateDB Gene IDBG-77813 (SPOCK2)
Protein Structure
UniProt Annotation
Function May participate in diverse steps of neurogenesis. Binds calcium.
Subcellular Localization Secreted, extracellular space, extracellular matrix {ECO:0000305}.
Disease Associations
Tissue Specificity Highly expressed in brain. Also found in lung and testis. {ECO:0000269PubMed:10386950}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0007416 synapse assembly
GO:0030198 extracellular matrix organization
GO:0045595 regulation of cell differentiation
Cellular Component
GO:0005578 proteinaceous extracellular matrix
Protein Structure and Domains
PDB ID
InterPro IPR000716 Thyroglobulin type-1
IPR002350 Kazal domain
IPR019577 SPARC/Testican, calcium-binding domain
PFAM PF00086
PF00050
PF07648
PF10591
PRINTS
PIRSF
SMART SM00211
SM00280
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q92563
PhosphoSite PhosphoSite-Q92563
TrEMBL B4DFA9
UniProt Splice Variant
Entrez Gene 9806
UniGene Hs.623618
RefSeq NP_055582
HUGO HGNC:13564
OMIM 607988
CCDS CCDS7313
HPRD 12146
IMGT
EMBL AC022392 AJ001453 AK294008 AK307091 AY358921 BC023558 D87465
GenPept AAH23558 AAQ89280 BAA13404 BAG57370 CAA04774