Version 5.4
Homo sapiens Protein: SPOCK2
Summary
InnateDB Protein IDBP-77817.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPOCK2
Protein Name sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
Synonyms testican-2;
Species Homo sapiens
Ensembl Protein ENSP00000362201
InnateDB Gene IDBG-77813 (SPOCK2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005539 glycosaminoglycan binding
GO:0050840 extracellular matrix binding
Biological Process
GO:0007165 signal transduction
GO:0007416 synapse assembly
GO:0010811 positive regulation of cell-substrate adhesion
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
GO:0030198 extracellular matrix organization
GO:0045595 regulation of cell differentiation
Cellular Component
GO:0005578 proteinaceous extracellular matrix
Protein Structure and Domains
PDB ID
InterPro IPR000716 Thyroglobulin type-1
IPR002350 Kazal domain
IPR019577 SPARC/Testican, calcium-binding domain
PFAM PF00086
PF00050
PF07648
PF10591
PRINTS
PIRSF
SMART SM00211
SM00280
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q92563
PhosphoSite PhosphoSite-Q92563
TrEMBL B4DFA9
UniProt Splice Variant
Entrez Gene 9806
UniGene Hs.623618
RefSeq NP_001231879
HUGO HGNC:13564
OMIM 607988
CCDS CCDS7313
HPRD 12146
IMGT
EMBL AC022392 AJ001453 AK294008 AK307091 AY358921 BC023558 D87465
GenPept AAH23558 AAQ89280 BAA13404 BAG57370 CAA04774

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca