InnateDB Protein
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IDBP-77825.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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GTF3C3
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Protein Name
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general transcription factor IIIC, polypeptide 3, 102kDa
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Synonyms
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TFIIIC102; TFiiiC2-102; TFIIICgamma;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000263956
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InnateDB Gene
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IDBG-77823 (GTF3C3)
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Protein Structure
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Function |
Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters.
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Subcellular Localization |
Nucleus.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
37
[view]
|
Protein-Protein |
36
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
1
[view]
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0006351
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transcription, DNA-templated
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GO:0006383
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transcription from RNA polymerase III promoter
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GO:0010467
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gene expression
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GO:0042791
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5S class rRNA transcription from RNA polymerase III type 1 promoter
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GO:0042797
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tRNA transcription from RNA polymerase III promoter
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Cellular Component |
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PDB ID |
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InterPro |
IPR013026
Tetratricopeptide repeat-containing domain
IPR019734
Tetratricopeptide repeat
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PFAM |
PF13174
PF13176
PF13181
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PRINTS |
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PIRSF |
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SMART |
SM00028
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TIGRFAMs |
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Modification |
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SwissProt |
Q9Y5Q9
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PhosphoSite |
PhosphoSite-Q9Y5Q9
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
9330
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UniGene |
Hs.737375
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RefSeq |
NP_036218
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HUGO |
HGNC:4666
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OMIM |
604888
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CCDS |
CCDS2316
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HPRD |
11997
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IMGT |
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EMBL |
AC012486
AF133123
AF465407
AK027050
AK314718
AL137453
BC015995
BC043347
CH471063
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GenPept |
AAD41475
AAH15995
AAH43347
AAL73493
AAX88853
BAB15638
BAG37262
CAB70745
EAW70132
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