Homo sapiens Protein: WFDC8
Summary
InnateDB Protein IDBP-77874.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WFDC8
Protein Name WAP four-disulfide core domain 8
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000361735
InnateDB Gene IDBG-77872 (WFDC8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed ubiquitously, the highest levels are found in the epididymis followed by testis and trachea.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0030414 peptidase inhibitor activity
Biological Process
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR002223 Proteinase inhibitor I2, Kunitz metazoa
IPR008197 Whey acidic protein-type 4-disulphide core
PFAM PF00014
PF00095
PRINTS PR00759
PR00003
PIRSF
SMART SM00131
SM00217
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IUA0
PhosphoSite PhosphoSite-Q8IUA0
TrEMBL
UniProt Splice Variant
Entrez Gene 90199
UniGene Hs.116128
RefSeq NP_852611
HUGO HGNC:16163
OMIM
CCDS CCDS13361
HPRD 11685
IMGT
EMBL AF492015 AF492016 AL031663 AL121778 AL591715 CH471077
GenPept AAN70997 AAN70998 CAC39449 CAI21403 CAI22977 EAW75828 EAW75829