Version 5.4
| Homo sapiens Protein: OIT3 | |||||||
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| Summary | |||||||
| InnateDB Protein | IDBP-78010.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | OIT3 | ||||||
| Protein Name | oncoprotein induced transcript 3 | ||||||
| Synonyms | |||||||
| Species | Homo sapiens | ||||||
| Ensembl Protein | ENSP00000333900 | ||||||
| InnateDB Gene | IDBG-78008 (OIT3) | ||||||
| Protein Structure |
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| UniProt Annotation | |||||||
| Function | May be involved in hepatocellular function and development. {ECO:0000269PubMed:12939600}. | ||||||
| Subcellular Localization | Nucleus envelope {ECO:0000269PubMed:12939600}. Note=Can be secreted into blood. | ||||||
| Disease Associations | |||||||
| Tissue Specificity | Liver-specific. Expressed only in the hepatocytes. Down-regulated in hepatocellular carcinoma (HCC) and HCC cell lines. {ECO:0000269PubMed:12939600}. | ||||||
| Comments | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||
| PDB ID | |||||||
| InterPro |
IPR000742
Epidermal growth factor-like domain IPR001507 Zona pellucida domain IPR001881 EGF-like calcium-binding domain |
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| PFAM |
PF00008
PF00100 PF07645 |
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| PRINTS |
PR00023
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| PIRSF | |||||||
| SMART |
SM00181
SM00241 SM00179 |
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| TIGRFAMs | |||||||
| Post-translational Modifications | |||||||
| Modification | |||||||
| Cross-References | |||||||
| SwissProt | Q8WWZ8 | ||||||
| PhosphoSite | PhosphoSite-Q8WWZ8 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 170392 | ||||||
| UniGene | Hs.8366 | ||||||
| RefSeq | NP_689848 | ||||||
| HUGO | HGNC:29953 | ||||||
| OMIM | 609330 | ||||||
| CCDS | CCDS7318 | ||||||
| HPRD | 17660 | ||||||
| IMGT | |||||||
| EMBL | AK096435 AY013707 AY358339 BC126440 | ||||||
| GenPept | AAG40096 AAI26441 AAQ88705 BAC04788 | ||||||