Version 5.4
Homo sapiens Protein: PLA2G12B
Summary
InnateDB Protein IDBP-78033.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLA2G12B
Protein Name phospholipase A2, group XIIB
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000362123
InnateDB Gene IDBG-78031 (PLA2G12B)
Protein Structure
UniProt Annotation
Function Not known; does not seem to have catalytic activity.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Strong expression in liver, small intestine and kidney. {ECO:0000269PubMed:14516201}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004623 phospholipase A2 activity
GO:0005509 calcium ion binding
Biological Process
GO:0016042 lipid catabolic process
GO:0042632 cholesterol homeostasis
GO:0070328 triglyceride homeostasis
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR010711 Phospholipase A2, group XII secretory
IPR016090 Phospholipase A2 domain
PFAM PF06951
PF00068
PRINTS
PIRSF
SMART SM00085
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BX93
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 84647
UniGene
RefSeq NP_115951
HUGO HGNC:18555
OMIM 611653
CCDS CCDS7319
HPRD 10155
IMGT
EMBL AF339053 AF349540 AY358032 BC093996 BC111946 BC143532 CH471083
GenPept AAH93996 AAI11947 AAI43533 AAK30168 AAL09472 AAQ92918 EAW54466

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca