Version 5.4
Homo sapiens Protein: NIF3L1
Summary
InnateDB Protein IDBP-78343.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NIF3L1
Protein Name NIF3 NGG1 interacting factor 3-like 1 (S. pombe)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000352711
InnateDB Gene IDBG-78341 (NIF3L1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 84 experimentally validated interaction(s) in this database.
Experimentally validated
Total 84 [view]
Protein-Protein 84 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003934 GTP cyclohydrolase I activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0008134 transcription factor binding
GO:0046872 metal ion binding
Biological Process
GO:0035998 7,8-dihydroneopterin 3'-triphosphate biosynthetic process
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR002678 GTP cyclohydrolase 1 type 2/Nif3
IPR017222 GTP cyclohydrolase 1 type 2/Nif3, eukaryotic
PFAM PF01784
PRINTS
PIRSF PIRSF037490
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9GZT8
PhosphoSite PhosphoSite-Q9GZT8
TrEMBL Q658J0
UniProt Splice Variant
Entrez Gene 60491
UniGene
RefSeq NP_068596
HUGO HGNC:13390
OMIM 605778
CCDS CCDS42797
HPRD 10424
IMGT
EMBL AB038949 AC005037 AF060513 AF182416 AF283538 AK023378 AL834430 AY251943 BC007654 CH471063
GenPept AAG14952 AAG43131 AAG44846 AAH07654 AAP84063 AAY14724 BAB14551 BAB32499 CAH56370 EAW70224 EAW70225 EAW70227

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca