InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SEC61B

Summary

InnateDB Protein

IDBP-78555.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SEC61B

Protein Name

Sec61 beta subunit

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000223641

InnateDB Gene

IDBG-78553 (SEC61B)

Protein Structure

UniProt Annotation

Function

Necessary for protein translocation in the endoplasmic reticulum.

Subcellular Localization

Endoplasmic reticulum membrane; Single-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding
GO:0048408	epidermal growth factor binding

Biological Process

GO:0000060	protein import into nucleus, translocation
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0006412	translation
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0030433	ER-associated ubiquitin-dependent protein catabolic process
GO:0030970	retrograde protein transport, ER to cytosol
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0044267	cellular protein metabolic process