InnateDB Protein
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IDBP-78653.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TRAK2
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Protein Name
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trafficking protein, kinesin binding 2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000328875
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InnateDB Gene
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IDBG-78651 (TRAK2)
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Protein Structure
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Function |
May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR. {ECO:0000250}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}. Early endosome {ECO:0000250}. Mitochondrion {ECO:0000250}. Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner (By similarity). {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Widely expressed, with highest expression in heart.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
5
[view]
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Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR006933
HAP1, N-terminal
IPR022154
Trafficking kinesin-binding protein domain
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PFAM |
PF04849
PF12448
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O60296
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PhosphoSite |
PhosphoSite-O60296
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TrEMBL |
Q53TT7
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UniProt Splice Variant |
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Entrez Gene |
66008
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UniGene |
Hs.703496
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RefSeq |
NP_055864
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HUGO |
HGNC:13206
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OMIM |
607334
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CCDS |
CCDS2347
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HPRD |
09547
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IMGT |
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EMBL |
AB011121
AB038951
AB038964
AC007256
AC007282
AC080069
AK054763
BC017999
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GenPept |
AAH17999
AAX93196
AAY24227
BAA25475
BAB32501
BAB32550
BAB70803
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