InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Prmt5

Summary

InnateDB Protein

IDBP-787788.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Prmt5

Protein Name

protein arginine N-methyltransferase 5

Synonyms

Jbp1; Skb1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000138549

InnateDB Gene

IDBG-161405 (Prmt5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 89 interaction(s) predicted by orthology.

Experimentally validated
Total	29 [view]
Protein-Protein	28 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	89 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0008168	methyltransferase activity
GO:0008469	histone-arginine N-methyltransferase activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine
GO:0034969	histone arginine methylation
GO:0035246	peptidyl-arginine N-methylation

Cellular Component

GO:0005634	nucleus
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

MGI:1351645

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

S4R295

UniProt Splice Variant

Entrez Gene

27374

UniGene

RefSeq

MGI ID

MGI Symbol

Prmt5

OMIM

CCDS

HPRD

IMGT

EMBL

AC164433 CH466535

GenPept

EDL36343