Version 5.4
Mus musculus Protein: Npy2r
Summary
InnateDB Protein IDBP-788099.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Npy2r
Protein Name neuropeptide Y receptor Y2
Synonyms NPY2-R;
Species Mus musculus
Ensembl Protein ENSMUSP00000138282
InnateDB Gene IDBG-154454 (Npy2r)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001601 peptide YY receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0004983 neuropeptide Y receptor activity
Biological Process
GO:0001662 behavioral fear response
GO:0002793 positive regulation of peptide secretion
GO:0003151 outflow tract morphogenesis
GO:0003214 cardiac left ventricle morphogenesis
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007218 neuropeptide signaling pathway
GO:0007263 nitric oxide mediated signal transduction
GO:0030818 negative regulation of cAMP biosynthetic process
GO:0031645 negative regulation of neurological system process
GO:0033603 positive regulation of dopamine secretion
GO:0045785 positive regulation of cell adhesion
GO:0045987 positive regulation of smooth muscle contraction
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep
GO:0046903 secretion
GO:0051048 negative regulation of secretion
GO:0051930 regulation of sensory perception of pain
GO:0051967 negative regulation of synaptic transmission, glutamatergic
GO:0090394 negative regulation of excitatory postsynaptic membrane potential
GO:2000252 negative regulation of feeding behavior
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:108418
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000611 Neuropeptide Y receptor family
IPR001358 Neuropeptide Y2 receptor
IPR005395 Neuropeptide FF receptor family
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx
PFAM PF00001
PF10320
PRINTS PR00237
PR01012
PR01014
PR01570
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P97295
PhosphoSite PhosphoSite-P97295
TrEMBL
UniProt Splice Variant
Entrez Gene 18167
UniGene
RefSeq
MGI ID
MGI Symbol Npy2r
OMIM
CCDS CCDS59646
HPRD
IMGT
EMBL AC091478 AK049892 BC104490 BC104734 CH466547 D86238
GenPept AAI04491 AAI04735 BAA13050 BAC33975 EDL15430 EDL15431

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca