Version 5.4
Mus musculus Protein: Dnajb2
Summary
InnateDB Protein IDBP-788566.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dnajb2
Protein Name DnaJ (Hsp40) homolog, subfamily B, member 2
Synonyms 2700059H22Rik; Dnajb10; Hsj1; mDj8;
Species Mus musculus
Ensembl Protein ENSMUSP00000140566
InnateDB Gene IDBG-170401 (Dnajb2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030544 Hsp70 protein binding
GO:0031593 polyubiquitin binding
GO:0051082 unfolded protein binding
GO:0051087 chaperone binding
GO:0070628 proteasome binding
Biological Process
GO:0008285 negative regulation of cell proliferation
GO:0030308 negative regulation of cell growth
GO:0030433 ER-associated ubiquitin-dependent protein catabolic process
GO:0031398 positive regulation of protein ubiquitination
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0042026 protein refolding
GO:0090084 negative regulation of inclusion body assembly
GO:0090086 negative regulation of protein deubiquitination
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005829 cytosol
GO:0016234 inclusion body
Protein Structure and Domains
PDB ID MGI:1928739
InterPro IPR001623 DnaJ domain
IPR003903 Ubiquitin interacting motif
PFAM PF00226
PF02809
PRINTS PR00625
PIRSF
SMART SM00271
SM00726
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3TB24
UniProt Splice Variant
Entrez Gene 56812
UniGene
RefSeq NP_001153355
MGI ID
MGI Symbol Dnajb2
OMIM
CCDS
HPRD
IMGT
EMBL AK156083 AK171494
GenPept BAE33579 BAE42490

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca