Version 5.4
Mus musculus Protein: Bckdhb
Summary
InnateDB Protein IDBP-788592.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bckdhb
Protein Name branched chain ketoacid dehydrogenase E1, beta polypeptide
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000139684
InnateDB Gene IDBG-188832 (Bckdhb)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003826 alpha-ketoacid dehydrogenase activity
GO:0003863 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity
GO:0005515 protein binding
GO:0032403 protein complex binding
Biological Process
GO:0007584 response to nutrient
GO:0008152 metabolic process
GO:0009063 cellular amino acid catabolic process
GO:0009083 branched-chain amino acid catabolic process
GO:0051384 response to glucocorticoid
GO:0051591 response to cAMP
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex
Protein Structure and Domains
PDB ID MGI:88137
InterPro IPR005475 Transketolase-like, pyrimidine-binding domain
IPR005476 Transketolase, C-terminal
IPR009014 Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II
IPR029061 Thiamin diphosphate-binding fold
PFAM PF02779
PF02780
PRINTS
PIRSF
SMART SM00861
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 12040
UniGene
RefSeq XP_006510848
MGI ID
MGI Symbol Bckdhb
OMIM
CCDS
HPRD
IMGT
EMBL BC064099 L16992
GenPept AAH64099

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca