InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pim2

Summary

InnateDB Protein

IDBP-788788.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pim2

Protein Name

proviral integration site 2

Synonyms

DXCch3; Pim-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000140602

InnateDB Gene

IDBG-129634 (Pim2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0016773	phosphotransferase activity, alcohol group as acceptor

Biological Process

GO:0000082	G1/S transition of mitotic cell cycle
GO:0006468	protein phosphorylation
GO:0008285	negative regulation of cell proliferation
GO:0008637	apoptotic mitochondrial changes
GO:0009103	lipopolysaccharide biosynthetic process
GO:0009615	response to virus
GO:0043066	negative regulation of apoptotic process

Cellular Component

GO:0016020

membrane

Protein Structure and Domains

PDB ID

MGI:97587

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR010440 Lipopolysaccharide kinase
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714
PF06293

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt