InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fli1

Summary

InnateDB Protein

IDBP-788799.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fli1

Protein Name

Friend leukemia integration 1

Synonyms

EWSR2; Fli-1; SIC-1; Sic1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000138984

InnateDB Gene

IDBG-147469 (Fli1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	2 [view]
Protein-DNA	5 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003682	chromatin binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0008015	blood circulation
GO:0009887	organ morphogenesis
GO:0009987	cellular process
GO:0035855	megakaryocyte development

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:95554

InterPro

IPR003118 Pointed domain
IPR013761 Sterile alpha motif/pointed domain

PFAM

PF02198

PRINTS

PIRSF

SMART

SM00251

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

V9GX50

UniProt Splice Variant

Entrez Gene

14247

UniGene

RefSeq

MGI ID

MGI Symbol

Fli1

OMIM

CCDS

HPRD

IMGT

EMBL

AC127581 AC141646

GenPept