InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fhl2

Summary

InnateDB Protein

IDBP-788828.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fhl2

Protein Name

four and a half LIM domains 2

Synonyms

FHL-2; SLIM-3; SLIM3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000141170

InnateDB Gene

IDBG-149554 (Fhl2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 68 interaction(s) predicted by orthology.

Experimentally validated
Total	14 [view]
Protein-Protein	13 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	68 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0008270	zinc ion binding
GO:0042802	identical protein binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001649	osteoblast differentiation
GO:0006351	transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0009725	response to hormone
GO:0043066	negative regulation of apoptotic process
GO:0045892	negative regulation of transcription, DNA-templated
GO:0055014	atrial cardiac muscle cell development
GO:0055015	ventricular cardiac muscle cell development
GO:0060347	heart trabecula formation

Cellular Component

GO:0005634	nucleus
GO:0005925	focal adhesion
GO:0015629	actin cytoskeleton
GO:0030018	Z disc
GO:0031430	M band

Protein Structure and Domains

PDB ID

MGI:1338762

InterPro

IPR001781 Zinc finger, LIM-type

PFAM

PF00412

PRINTS

PIRSF

SMART

SM00132

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q543D7

UniProt Splice Variant

Entrez Gene

14200

UniGene

RefSeq

MGI ID

MGI Symbol

Fhl2

OMIM

CCDS

CCDS14922

HPRD

IMGT

EMBL

AF055889 AF114381 AF153340 AK052936 AK147024 CH466589 U77040

GenPept

AAB19211 AAC12770 AAD34170 AAD53230 BAC35211 BAE27617 EDK96913 EDK96914