InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Htr2c

Summary

InnateDB Protein

IDBP-789406.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Htr2c

Protein Name

5-hydroxytryptamine (serotonin) receptor 2C

Synonyms

5-HT2C; 5-HT2cR; 5-HTR2C; 5HT1c; Htr1c; SR1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000138772

InnateDB Gene

IDBG-177388 (Htr2c)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0004993	serotonin receptor activity
GO:0051378	serotonin binding

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007210	serotonin receptor signaling pathway
GO:0007626	locomotory behavior
GO:0007631	feeding behavior

Cellular Component

GO:0005887	integral component of plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:96281

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000377 5-Hydroxytryptamine 2C receptor
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx

PFAM

PF00001
PF10320

PRINTS

PR00237
PR00517

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite