InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nlrp6

Summary

InnateDB Protein

IDBP-789858.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nlrp6

Protein Name

NLR family, pyrin domain containing 6

Synonyms

AI504961; Avr; Nalp6; Navr; Navr/Avr; Pypaf5;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000139170

InnateDB Gene

IDBG-211907 (Nlrp6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005524	ATP binding

Biological Process

GO:0009617	response to bacterium
GO:0034122	negative regulation of toll-like receptor signaling pathway
GO:0042060	wound healing
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043409	negative regulation of MAPK cascade
GO:0050727	regulation of inflammatory response
GO:0050777	negative regulation of immune response

Cellular Component

GO:0005575

cellular_component

Protein Structure and Domains

PDB ID

MGI:2141990

InterPro

IPR003590 Leucine-rich repeat, ribonuclease inhibitor subtype
IPR004020 DAPIN domain
IPR007111 NACHT nucleoside triphosphatase
IPR011029 Death-like domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF02758

PRINTS

PIRSF

SMART

SM00368

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F8UKQ6

UniProt Splice Variant

Entrez Gene

101613

UniGene

RefSeq

MGI ID

MGI Symbol

Nlrp6

OMIM

CCDS

HPRD

IMGT

EMBL

AC107815 AC162287 JF810536

GenPept

AEI54131