Version 5.4
Mus musculus Protein: Scn1b
Summary
InnateDB Protein IDBP-790350.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Scn1b
Protein Name sodium channel, voltage-gated, type I, beta
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000139680
InnateDB Gene IDBG-172430 (Scn1b)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019871 sodium channel inhibitor activity
GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential
GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential
Biological Process
GO:0007411 axon guidance
GO:0010765 positive regulation of sodium ion transport
GO:0010976 positive regulation of neuron projection development
GO:0019227 neuronal action potential propagation
GO:0021966 corticospinal neuron axon guidance
GO:0035725 sodium ion transmembrane transport
GO:0040011 locomotion
GO:0046684 response to pyrethroid
GO:0060048 cardiac muscle contraction
GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization
GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization
GO:0061337 cardiac conduction
GO:0086002 cardiac muscle cell action potential involved in contraction
GO:0086012 membrane depolarization during cardiac muscle cell action potential
GO:0086047 membrane depolarization during Purkinje myocyte cell action potential
GO:0086091 regulation of heart rate by cardiac conduction
GO:2000649 regulation of sodium ion transmembrane transporter activity
Cellular Component
GO:0001518 voltage-gated sodium channel complex
GO:0014704 intercalated disc
GO:0030315 T-tubule
GO:0033268 node of Ranvier
GO:0034706 sodium channel complex
Protein Structure and Domains
PDB ID MGI:98247
InterPro IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin
PFAM PF07686
PF00047
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 20266
UniGene
RefSeq XP_006539756
MGI ID
MGI Symbol Scn1b
OMIM
CCDS CCDS21126
HPRD
IMGT
EMBL BC009652 BC039140 U46681 U85786
GenPept AAB49368 AAC53006 AAH09652 AAH39140

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca