InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Uchl5

Summary

InnateDB Protein

IDBP-790374.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Uchl5

Protein Name

ubiquitin carboxyl-terminal esterase L5

Synonyms

5830413B11Rik; Uch37;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000140106

InnateDB Gene

IDBG-197081 (Uchl5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 156 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	156 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004221	ubiquitin thiolesterase activity
GO:0004843	ubiquitin-specific protease activity
GO:0004866	endopeptidase inhibitor activity
GO:0005515	protein binding
GO:0008242	omega peptidase activity
GO:0044822	poly(A) RNA binding
GO:0070628	proteasome binding

Biological Process

GO:0006281	DNA repair
GO:0006310	DNA recombination
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0010951	negative regulation of endopeptidase activity
GO:0016579	protein deubiquitination
GO:0021670	lateral ventricle development
GO:0030901	midbrain development
GO:0048853	forebrain morphogenesis
GO:0061136	regulation of proteasomal protein catabolic process

Cellular Component

GO:0000502	proteasome complex
GO:0005622	intracellular
GO:0005634	nucleus
GO:0005829	cytosol
GO:0031011	Ino80 complex

Protein Structure and Domains

PDB ID

MGI:1914848

InterPro

IPR001578 Peptidase C12, ubiquitin carboxyl-terminal hydrolase
IPR017390 Ubiquitinyl hydrolase, UCH37 type

PFAM

PF01088

PRINTS

PR00707

PIRSF

PIRSF038120

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

56207

UniGene

RefSeq

NP_062508

MGI ID

MGI Symbol

Uchl5

OMIM

CCDS

CCDS15346

HPRD

IMGT

EMBL

AF148447 AF175903 AK007860 AK011117 AK017925 BC006891

GenPept

AAD31534 AAD50311 AAH06891 BAB25312 BAB27412 BAB31005