InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Eya1

Summary

InnateDB Protein

IDBP-790384.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Eya1

Protein Name

eyes absent 1 homolog (Drosophila)

Synonyms

bor;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000141112

InnateDB Gene

IDBG-134456 (Eya1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	22 [view]
Protein-Protein	16 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	6 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0004725	protein tyrosine phosphatase activity
GO:0005515	protein binding
GO:0046872	metal ion binding

Biological Process

GO:0000132	establishment of mitotic spindle orientation
GO:0001656	metanephros development
GO:0001657	ureteric bud development
GO:0001658	branching involved in ureteric bud morphogenesis
GO:0003151	outflow tract morphogenesis
GO:0006302	double-strand break repair
GO:0006351	transcription, DNA-templated
GO:0006470	protein dephosphorylation
GO:0007275	multicellular organismal development
GO:0007389	pattern specification process
GO:0007501	mesodermal cell fate specification
GO:0009887	organ morphogenesis
GO:0010212	response to ionizing radiation
GO:0014706	striated muscle tissue development
GO:0016576	histone dephosphorylation
GO:0016925	protein sumoylation
GO:0034613	cellular protein localization
GO:0035088	establishment or maintenance of apical/basal cell polarity
GO:0035335	peptidyl-tyrosine dephosphorylation
GO:0035909	aorta morphogenesis
GO:0042472	inner ear morphogenesis
GO:0042473	outer ear morphogenesis
GO:0042474	middle ear morphogenesis
GO:0045165	cell fate commitment
GO:0045664	regulation of neuron differentiation
GO:0045739	positive regulation of DNA repair
GO:0045747	positive regulation of Notch signaling pathway
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048665	neuron fate specification
GO:0048704	embryonic skeletal system morphogenesis
GO:0048752	semicircular canal morphogenesis
GO:0048856	anatomical structure development
GO:0050679	positive regulation of epithelial cell proliferation
GO:0060037	pharyngeal system development
GO:0060487	lung epithelial cell differentiation
GO:0071599	otic vesicle development
GO:0071600	otic vesicle morphogenesis
GO:0072513	positive regulation of secondary heart field cardioblast proliferation
GO:0090103	cochlea morphogenesis
GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand