InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fat1

Summary

InnateDB Protein

IDBP-790414.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fat1

Protein Name

FAT tumor suppressor homolog 1 (Drosophila)

Synonyms

2310038E12Rik; AU023433; Fath; mFat1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000140596

InnateDB Gene

IDBG-151656 (Fat1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0007015	actin filament organization
GO:0007156	homophilic cell adhesion
GO:0007163	establishment or maintenance of cell polarity
GO:0016337	single organismal cell-cell adhesion

Cellular Component

GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0005911	cell-cell junction
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030027	lamellipodium
GO:0030054	cell junction
GO:0030175	filopodium
GO:0048471	perinuclear region of cytoplasm
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:109168

InterPro

IPR000742 Epidermal growth factor-like domain
IPR001791 Laminin G domain
IPR001881 EGF-like calcium-binding domain
IPR002126 Cadherin
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR015919 Cadherin-like

PFAM

PF00008
PF00054
PF02210
PF07645
PF00028

PRINTS

PR00205

PIRSF

SMART

SM00181
SM00210
SM00282
SM00179
SM00112

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt