Version 5.4
Homo sapiens Protein: TMEM35
Summary
InnateDB Protein IDBP-79478.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM35
Protein Name transmembrane protein 35
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000362021
InnateDB Gene IDBG-79476 (TMEM35)
Protein Structure
UniProt Annotation
Function A soluble peptide released by shedding may interact with NGFR and modulate neurite outgrowth. {ECO:0000250}.
Subcellular Localization Peroxisome membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Note=Shedding may lead to a soluble peptide. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005778 peroxisomal membrane
GO:0016021 integral component of membrane
GO:0016023 cytoplasmic membrane-bounded vesicle
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q53FP2
PhosphoSite PhosphoSite-Q53FP2
TrEMBL
UniProt Splice Variant
Entrez Gene 59353
UniGene Hs.607943
RefSeq NP_067650
HUGO HGNC:25864
OMIM
CCDS CCDS14478
HPRD 06523
IMGT
EMBL AK024146 AK223240 AL109952 BC050273 BC078658
GenPept AAH50273 AAH78658 BAB14840 BAD96960 CAI43000

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca