InnateDB Protein
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IDBP-79572.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TAF7L
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Protein Name
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TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000349235
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InnateDB Gene
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IDBG-79564 (TAF7L)
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Protein Structure
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Function |
Probably functions as a spermatogensis-specific component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May play a role in spermatogenesis (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Cytoplasmic in spermatogonia and early spermatocytes (preleptotene, leptotene, and zygotene); translocates into the nuclei of pachytene spermatocytes and round spermatids. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Testis-specific. {ECO:0000269PubMed:11279525}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
6
[view]
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Protein-Protein |
6
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR006751
TAFII55 protein, conserved region
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PFAM |
PF04658
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q5H9L4
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PhosphoSite |
PhosphoSite-Q5H9L4
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
54457
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UniGene |
Hs.223806
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RefSeq |
NP_001161946
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HUGO |
HGNC:11548
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OMIM |
300314
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CCDS |
CCDS55466
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HPRD |
02259
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IMGT |
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EMBL |
AF285595
AK026810
AL109801
BC043391
CH471115
Z68331
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GenPept |
AAH43391
AAK31974
BAB15560
CAI42014
CAI42015
CAI42017
CAI43034
CAI43035
CAI43036
EAX02847
EAX02848
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